Answer
Users can use SPI for bootloading as well as UART. Our datasheet only mentions the UART Mode because that is what our development board is setup to use. With that in mind, we expect most users to use the bootloader in UART Mode as opposed to SPI. However, users are welcome to use either the UART or SPI Mode. The SaBLE-x module exposes every IO pin of the CC2640, which means users can use any of the CC2640 features detailed in the TI datasheet/technical reference manual.