Which out of the box hardware can be used to externally debug and flash Lyra modules via the Serial Wire Debug (SWD) interface in development and production stage?

In order to debug and program our Lyra (22) and 24 modules externally via the Serial Wire Debug (SWD) interface in development or production stage, we recommend using the Simplicity Link Debugger (BRD1015A) board for example or any SLWSTK* part number which is listed under https://www.silabs.com/development-tools (Starter Kits) that comes with an onboard SEGGER J-Link debugger and debug out functionality.

Of course, it is also possible to use a debug probe from SEGGER directly or any other SEGGER compatible hardware with no vendor lock which does support EFR32BG22* and EFR32BG24* target devices / SoCs. See https://www.segger.com/supported-devices/silicon-labs/blue-gecko for more details and an overview.